TERJEMAHAN AL-QURAN

QURAN TRANSLATION

sToRy Of My LiFe..

How my life goes.. People don't know the process n the flow. People always intend to misjudge me. I just don't understand why.. This is one of the ultimate reasons for me to share this blog with those who really need to get to know me better and would like to see the different view of life. All I have here is just to express what I could, from my experiences and things, people that I love. Looks rather simple, but trust me, it is very tough!! Venture down my words and nurture the good once out and save the undesired once, probably for a second opinion. Enjoy your readings!! CHIEF MAFIA

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11.5.12

I'M A SUSPECT!!

About a month ago, our company had organized a Health Check for Managers & Officers. Fortunately I was one of the chosen ones. :) Went thru d check-up with a waive of RM120 [sponsored by co.]. It was fun!!

Last week, we received our RESULTS!! ^_^ I went thru the report, to me everything was fine. [I repeat ya.. "TO ME"..] But the fact it was quite awful. Hehehe.. They had names of check-ups done and all the contents. There were a few terms that were typed in BOLD fonts. I supposed that those BOLD fonts simply means I'm in trouble!! = = '

Other than those bold fonts all over the report, there was this phrase highlighted in pink : to rule out haemoglobinopathy <-- exactly like dis!! Frankly speaking, I seriously did not see that marking when I read d report at home d other day. @_@ Niway, the doctor's explanation after explanation came to this final statment, "We suspect you have Thalassemia".. I was shocked but I was expressionless. :)

So let's read this article down here~ Enjoy!!
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Thalassemia is a blood disorder passed down through families (inherited) in which the body makes an abnormal form of hemoglobin, the protein in red blood cells that carries oxygen. The disorder results in excessive destruction of red blood cells, which leads to anemia.

Causes, incidence, and risk factors

Hemoglobin is made of two proteins: Alpha globin and beta globin. Thalassemia occurs when there is a defect in a gene that helps control production of one of these proteins.

There are two main types of thalassemia:
1. Alpha thalassemia occurs when a gene or genes related to the alpha globin protein are missing or changed (mutated).
2. Beta thalassemia occurs when similar gene defects affect production of the beta globin protein.

Alpha thalassemias occur most commonly in persons from southeast Asia, the Middle East, China, and in those of African descent.
Beta thalassemias occur in persons of Mediterranean origin, and to a lesser extent, Chinese, other Asians, and African Americans.

There are many forms of thalassemia. Each type has many different subtypes. Both alpha and beta thalassemia include the following two forms:
1. Thalassemia major
2. Thalassemia minor

You must inherit the defective gene from both parents to develop thalassemia major.
Thalassemia minor occurs if you receive the defective gene from only one parent. Persons with this form of the disorder are carriers of the disease and usually do not have symptoms.

Beta thalassemia major is also called Cooley's anemia.

Risk factors for thalassemia include:
1. Asian, Chinese, Mediterranean, or African American ethnicity
2. Family history of the disorder

Symptoms

1. The most severe form of alpha thalassemia major causes stillbirth (death of the unborn baby during birth or the late stages of pregnancy).
2. Children born with thalessemia major (Cooley's anemia) are normal at birth, but develop severe anemia during the first year of life.

Other symptoms can include:

1. Bone deformities in the face
2. Fatigue
3. Growth failure
4. Shortness of breath
5. Yellow skin (jaundice)

Persons with the minor form of alpha and beta thalassemia have small red blood cells (which are identified by looking at their red blood cells under a microscope), but no symptoms.

Signs and tests

1. A physical exam may reveal a swollen (enlarged) spleen.
2. A blood sample will be taken and sent to a laboratory for examination.
3. Red blood cells will appear small and abnormally shaped when looked at under a microscope.
4. A complete blood count (CBC) reveals anemia.
5. A test called hemoglobin electrophoresis shows the presence of an abnormal form of hemoglobin.
6. A test called mutational analysis can help detect alpha thalassemia that cannot be seen with hemoglobin electrophoresis.

Treatment

Treatment for thalassemia major often involves regular blood transfusions and folate supplements.
If you receive blood transfusions, you should not take iron supplements. Doing so can cause a high amount of iron to build up in the body, which can be harmful.

Persons who receive significant numbers of blood transfusions need a treatment called chelation therapy to remove excess iron from the body.

Bone marrow transplant may help treat the disease in some patients, especially children.

Expectations (prognosis)

1. Severe thalassemia can cause early death due to heart failure a, usually between ages 20 and 30.
2. Frequent blood transfusions with therapy to remove iron from the body helps improve the outcome.
3. Less severe forms of thalassemia usually do not result in a shorter life span.
4. Genetic counseling and prenatal screening may be available to those with a family history of this condition who are planning to have children.

Complications

1. Untreated, thalassemia major leads to heart failure and liver problems, and makes a person more likely to develop infections.
2. Blood transfusions can help control some symptoms, but may result in too much iron which can damage the heart, liver, and endocrine system.
3. Calling your health care provider
4. Call for an appointment with your health care provider if:
5. You or your child has symptoms of thalassemia
6. You are being treated for the disorder and new symptoms develop

(ADAPTED FROM PUBMED HEALTH)

CHIEF

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